Suggest equally people and caregivers in regards to the pitfalls of respiratory melancholy and sedation when OXYCONTIN is utilised with benzodiazepines or other CNS depressants (together with Alcoholic beverages and illicit medication). Advise individuals to not push or function hefty equipment right up until the results of concomitant use of the benzodiazepine or other CNS depressant have already been established.
The formula for conversion from prior opioids, together with oral oxycodone, on the each day dose of OXYCONTIN is mg a day of prior opioid x aspect = mg every day of OXYCONTIN.
Tell people of the potential risk of lifetime-threatening respiratory melancholy, such as information and facts that the danger is biggest when setting up OXYCONTIN or when the dosage is amplified, and that it may possibly happen even at proposed dosages.
Instruct people to swallow OXYCONTIN tablets full; crushing, chewing, or dissolving OXYCONTIN tablets can cause immediate release and absorption of the potentially fatal dose of oxycodone [see WARNINGS AND PRECAUTIONS].
Productive versus severe agony like pain caused by most cancers. OxyContin is lengthy-Long lasting and only really should be taken twice per day.
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Because of the challenges related to accidental ingestion, misuse, and abuse, recommend patients to retailer OXYCONTIN securely, outside of sight and reach of kids, and in a location not available by Other individuals, such as website visitors to the home.
To inform friends and family about their naloxone and to help keep it in an area where by more info family and friends can entry it within an emergency
Before you begin having this medication, request your doctor or pharmacist if you must prevent or alter how you use your other opioid medication(s).
Accidental ingestion of even one particular dose of OXYCONTIN, Specially by small children, can result in respiratory depression and Dying on account of an overdose of oxycodone.
These strengths may well induce overdose (even Loss of life) if taken by a one who has not been often having opioids.Don't use the prolonged-release form of oxycodone to relieve ache that may be moderate or that could go away in a couple of days. This medication is not really for occasional ("as required") use.
Concomitant utilization of OXYCONTIN with CYP3A4 inducers or discontinuation of a CYP3A4 inhibitor could lessen oxycodone plasma concentrations, lessen opioid efficacy or, probably, cause a withdrawal syndrome inside of a affected person who had developed Actual physical dependence to oxycodone.
Just before taking oxycodone, notify your doctor or pharmacist if you are allergic to it; or to other opioid agony relievers (for instance website oxymorphone); or When you've got another allergic reactions.
Opioids are sought for nonmedical use and they are matter to diversion from reputable prescribed use. Take into account these risks when prescribing or dispensing OXYCONTIN. Approaches to scale back these risks incorporate prescribing the drug within the smallest acceptable amount and advising the affected person on very careful storage in read more the drug during the system of remedy and the proper disposal of unused drug.